pentobarbital will reduce the level or result of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Pitolisant exposure is lessened by 50% if coadministered with solid CYP3A4 inducers.
pentobarbital will decrease the level or result of donepezil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.
pentobarbital will decrease the level or outcome of verapamil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or outcome of levoketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will lower the level or result of parecoxib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Mysterious.
pentobarbital will lessen the extent or effect of tamoxifen by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.
pentobarbital will lower the level or influence of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
pentobarbital will decrease the level or outcome of lefamulin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Avoid coadministration of lefamulin with powerful or moderate CYP3A inducers Except the profit outweighs threats. Observe for reduced efficacy.
pentobarbital will minimize the extent or outcome of voriconazole by affecting hepatic enzyme CYP2C9/ten metabolism. Slight/Significance Unfamiliar.
pentobarbital will decrease the extent or result of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the level or result of midostaurin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Robust CYP3A4 inducers may well minimize midostaurin concentrations causing decreased efficacy.
lasmiditan, pentobarbital. Both boosts effects of another by sedation. Use Warning/Keep an eye on. Coadministration of lasmiditan together with other CNS depressant drugs, such as Alcoholic beverages more info have not been evaluated in scientific scientific studies. Lasmiditan could result in sedation, and also other cognitive and/or neuropsychiatric adverse reactions.
pentobarbital will minimize the level or outcome of alosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.
buprenorphine subdermal implant and pentobarbital both equally enhance sedation. Keep away from or Use Alternate Drug. Restrict use to clients for whom alternative cure possibilities are insufficient